Cargando…

Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin

The small leucine-rich proteoglycans (SLRPs) are important regulators of extracellular matrix assembly and cell signalling. We have determined crystal structures at ~ 2.2 Å resolution of human fibromodulin and chondroadherin, two collagen-binding SLRPs. Their overall fold is similar to that of the p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paracuellos, Patricia, Kalamajski, Sebastian, Bonna, Arkadiusz, Bihan, Dominique, Farndale, Richard W., Hohenester, Erhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618690/ https://www.ncbi.nlm.nih.gov/pubmed/28215822 http://dx.doi.org/10.1016/j.matbio.2017.02.002

Ejemplares similares

Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase
por: Kalamajski, Sebastian, et al.
Publicado: (2016)

Topological Analysis of Small Leucine-Rich Repeat Proteoglycan Nyctalopin
por: Bojang, Pasano, et al.
Publicado: (2012)

Small Leucine-Rich Proteoglycans (SLRPs) in the Retina
por: Low, Shermaine W. Y., et al.
Publicado: (2021)

The role of Tsukushi (TSK), a small leucine-rich repeat proteoglycan, in bone growth
por: Yano, Kosei, et al.
Publicado: (2017)

The matricellular functions of small leucine-rich proteoglycans (SLRPs)
por: Merline, Rosetta, et al.
Publicado: (2009)

Small Leucine-Rich Proteoglycans in Skin Wound Healing
por: Pang, Xiaoxiao, et al.
Publicado: (2020)

Association of chondroadherin with leiomyosarcoma
por: Gokce, Sefik, et al.
Publicado: (2023)

The Small Leucine-Rich Repeat Proteoglycan Biglycan Binds to α-Dystroglycan and Is Upregulated in Dystrophic Muscle
por: Bowe, Mark A., et al.
Publicado: (2000)

Small leucine rich proteoglycans, a novel link to osteoclastogenesis
por: Kram, Vardit, et al.
Publicado: (2017)

Small leucine-rich proteoglycans in physiological and biomechanical function of bone
por: Hua, Rui, et al.
Publicado: (2021)

Inhibitory Role of the Small Leucine-Rich Proteoglycan Biglycan in Bladder Cancer
por: Niedworok, Christian, et al.
Publicado: (2013)

The Skeletal Phenotype of Chondroadherin Deficient Mice
por: Hessle, Lovisa, et al.
Publicado: (2013)

Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site
por: Monfort, Jordi, et al.
Publicado: (2006)

Fibromodulin deficiency reduces collagen structural network but not glycosaminoglycan content in a syngeneic model of colon carcinoma
por: Olsson, P. Olof, et al.
Publicado: (2017)

Correction: Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease 13 - identification of a new biglycan cleavage site
por: Monfort, Jordi, et al.
Publicado: (2013)

Usurped SLRPs: novel arthritis biomarkers exposed by catabolism of small leucine-rich proteoglycans?
por: Flannery, Carl R
Publicado: (2006)

Modulation of small leucine-rich proteoglycans (SLRPs) expression in the mouse uterus by estradiol and progesterone
por: Salgado, Renato M, et al.
Publicado: (2011)

Small leucine-rich proteoglycans in atherosclerotic lesions: novel targets of chronic statin treatment?
por: Marzoll, Andrea, et al.
Publicado: (2011)

Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases
por: Zeng-Brouwers, Jinyang, et al.
Publicado: (2020)

Correction: The Skeletal Phenotype of Chondroadherin Deficient Mice
por: Hessle, Lovisa, et al.
Publicado: (2013)

An Activating Mutation Reveals a Second Binding Mode of the Integrin α2 I Domain to the GFOGER Motif in Collagens
por: Carafoli, Federico, et al.
Publicado: (2013)

The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling
por: Andenæs, Kine, et al.
Publicado: (2018)

Contaminants in commercial preparations of ‘purified’ small leucine-rich proteoglycans may distort mechanistic studies
por: Brown, Sharon J., et al.
Publicado: (2017)

Expression, localization and synthesis of small leucine-rich proteoglycans in developing mouse molar tooth germ
por: Randilini, Angammana, et al.
Publicado: (2020)

The Extracellular Small Leucine-Rich Proteoglycan Biglycan Is a Key Player in Gastric Cancer Aggressiveness
por: Pinto, Filipe, et al.
Publicado: (2021)

Roles of Two Small Leucine-Rich Proteoglycans Decorin and Biglycan in Pregnancy and Pregnancy-Associated Diseases
por: Halari, Chidambra D., et al.
Publicado: (2021)

The Landscape of Small Leucine-Rich Proteoglycan Impact on Cancer Pathogenesis with a Focus on Biglycan and Lumican
por: Berdiaki, Aikaterini, et al.
Publicado: (2023)

Insights into Collagen Uptake by C-type Mannose Receptors from the Crystal Structure of Endo180 Domains 1–4
por: Paracuellos, Patricia, et al.
Publicado: (2015)

Nanomechanical phenotype of chondroadherin-null murine articular cartilage
por: Batista, Michael A., et al.
Publicado: (2014)

Posterior Amorphous Corneal Dystrophy Is Associated with a Deletion of Small Leucine-rich Proteoglycans on Chromosome 12
por: Kim, Michelle J., et al.
Publicado: (2014)

Small leucine-rich proteoglycans (SLRPs) in the endometrium of polycystic ovary syndrome women: a pilot study
por: Simões, Ricardo Santos, et al.
Publicado: (2017)

Expression of minor cartilage collagens and small leucine rich proteoglycans may be relatively reduced in osteoarthritic cartilage
por: Tanaka, Nobuho, et al.
Publicado: (2019)

Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment
por: Kolb, Julia, et al.
Publicado: (2023)

Opticin, a small leucine-rich proteoglycan, is uniquely expressed and translocated to the nucleus of chronic lymphocytic leukemia cells
por: Mikaelsson, Eva, et al.
Publicado: (2013)

The Genes Encoding Small Leucine-Rich Proteoglycans Undergo Differential Expression Alterations in Colorectal Cancer, Depending on Tumor Location
por: Solis-Hernandez, Maria Pilar, et al.
Publicado: (2021)

Crystallographic Insight into Collagen Recognition by Discoidin Domain Receptor 2
por: Carafoli, Federico, et al.
Publicado: (2009)

Effects of mechanical stretching on the morphology of extracellular polymers and the mRNA expression of collagens and small leucine-rich repeat proteoglycans in vaginal fibroblasts from women with pelvic organ prolapse
por: Wang, Sumei, et al.
Publicado: (2018)

The small leucine-rich proteoglycan, biglycan, is highly expressed in adipose tissue of Psammomys obesus and is associated with obesity and type 2 diabetes
por: Bolton, Kristy, et al.
Publicado: (2012)

Abstract 15: The Role of Burn Tissue and Denatured Small Leucine Rich Proteoglycans in the Activation of the Toll-like Receptor 4 Pathway
por: Agrawal, Ambika, et al.
Publicado: (2019)

Editorial: The Physiology and Pharmacology of Leucine-rich Repeat GPCRs
por: Arey, Brian J., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_r6da2c2ek8juhvp0r7ksq9lo06