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Epigallocatechin gallate inhibits Streptococcus pneumoniae virulence by simultaneously targeting pneumolysin and sortase A

Streptococcus pneumoniae (pneumococcus), the causative agent of several human diseases, possesses numerous virulence factors associated with pneumococcal infection and pathogenesis. Pneumolysin (PLY), an important virulence factor, is a member of the cholesterol‐dependent cytolysin family and has cy...

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Detalles Bibliográficos
Autores principales: Song, Meng, Teng, Zihao, Li, Meng, Niu, Xiaodi, Wang, Jianfeng, Deng, Xuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618700/
https://www.ncbi.nlm.nih.gov/pubmed/28402019
http://dx.doi.org/10.1111/jcmm.13179