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Optogenetic Inhibition of Striatal Neuronal Activity Improves the Survival of Transplanted Neural Stem Cells and Neurological Outcomes after Ischemic Stroke in Mice
Neural stem cell (NSC) transplantation is a promising treatment to improve the recovery after brain ischemia. However, how the survival, proliferation, migration, and differentiation of implanted NSC are influenced by endogenous neuronal activity remains unclear. In this work, we used optogenetic te...
Autores principales: | Lu, Yifan, Jiang, Lu, Li, Wanlu, Qu, Meijie, Song, Yaying, He, Xiaosong, Zhang, Zhijun, Yang, Guo-Yuan, Wang, Yongting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618753/ https://www.ncbi.nlm.nih.gov/pubmed/29104593 http://dx.doi.org/10.1155/2017/4364302 |
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