Heme Oxygenase Induction Suppresses Hepatic Hepcidin and Rescues Ferroportin and Ferritin Expression in Obese Mice

Hepcidin, a phase II reactant secreted by hepatocytes, regulates cellular iron levels by increasing internalization of ferroportin-a transmembrane protein facilitating egress of cellular iron. Chronic low-grade inflammatory states, such as obesity, have been shown to increase oxidative stress and en...

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Detalles Bibliográficos
Autores principales: Puri, Nitin, Arefiev, Yevgeniy, Chao, Robert, Sacerdoti, David, Chaudry, Hibba, Nichols, Alexandra, Srikanthan, Krithika, Nawab, Athar, Sharma, Dana, Lakhani, Vishal Hari, Klug, Rebecca, Sodhi, Komal, Peterson, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618758/
https://www.ncbi.nlm.nih.gov/pubmed/29062571
http://dx.doi.org/10.1155/2017/4964571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618758/
https://www.ncbi.nlm.nih.gov/pubmed/29062571
http://dx.doi.org/10.1155/2017/4964571

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