β-Naphthoflavone-Induced Mitochondrial Respiratory Damage in Cyp1 Knockout Mouse and in Cell Culture Systems: Attenuation by Resveratrol Treatment

A number of xenobiotic-inducible cytochrome P450s (CYPs) are now known to be localized in the mitochondrial compartment, though their pharmacological or toxicological roles remain unclear. Here, we show that BNF treatment markedly inhibits liver mitochondrial O(2) consumption rate (OCR), ADP-depende...

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Detalles Bibliográficos
Autores principales: Anandasadagopan, Suresh Kumar, Singh, Naveen M., Raza, Haider, Bansal, Seema, Selvaraj, Venkatesh, Singh, Shilpee, Chowdhury, Anindya Roy, Leu, Nicolae Adrian, Avadhani, Narayan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618780/
https://www.ncbi.nlm.nih.gov/pubmed/29098061
http://dx.doi.org/10.1155/2017/5213186

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