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Targeted antigen delivery by an anti-class II MHC VHH elicits focused αMUC1(Tn) immunity

Unusual patterns of glycosylation on the surface of transformed cells contribute to immune modulation and metastasis of malignant tumors. Active immunization against them requires effective antigen presentation, which is complicated by a lack of access to tumor-specific posttranslational modificatio...

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Detalles Bibliográficos
Autores principales:	Fang, Tao, Van Elssen, Catharina H. M. J., Duarte, Joao N., Guzman, Jonathan S., Chahal, Jasdave S., Ling, Jingjing, Ploegh, Hidde L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2017
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618788/ https://www.ncbi.nlm.nih.gov/pubmed/28970938 http://dx.doi.org/10.1039/c7sc00446j

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