Cargando…
BCG-induced Disseminated Mycobacterial Infection of Skin and Bone in an Otherwise Immunocompetent Child
One 2-year-old undernourished girl presented to our outpatient with large erythematous scaly plaques in arm along with multiple bony swellings over nose, fingers, left foot, and back for the past 1 year. Apart from skin and bone lesions the girl was also had intermittent fever, pallor, irritability,...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618842/ https://www.ncbi.nlm.nih.gov/pubmed/28979017 http://dx.doi.org/10.4103/ijd.IJD_55_17 |
_version_ | 1783267275504091136 |
---|---|
author | De, Abhishek Sarkar, Sumantra Sharma, Nidhi Ansari, Asad Reja, Abu Hena Hasanoor Sarda, Aarti |
author_facet | De, Abhishek Sarkar, Sumantra Sharma, Nidhi Ansari, Asad Reja, Abu Hena Hasanoor Sarda, Aarti |
author_sort | De, Abhishek |
collection | PubMed |
description | One 2-year-old undernourished girl presented to our outpatient with large erythematous scaly plaques in arm along with multiple bony swellings over nose, fingers, left foot, and back for the past 1 year. Apart from skin and bone lesions the girl was also had intermittent fever, pallor, irritability, and malnourishment. Her parents gave a history of incomplete healing at the BCG vaccination site. The case was diagnosed to be case of disseminated mycobacterial infection skin and bone with the help of histopathology, radiological examination, and DNA polymerase chain reaction (PCR). DNA PCR from the skin lesion came positive for mycobacteria tuberculosis complex. The girl was treated with 6 months of standard antitubercular drug treatment with very good improvement not only of her cutaneous and bone changes but also of her general health and growth. We report the case because paucity of similar infection in literature and for greater recognition of potential epidemiological threat. |
format | Online Article Text |
id | pubmed-5618842 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-56188422017-10-04 BCG-induced Disseminated Mycobacterial Infection of Skin and Bone in an Otherwise Immunocompetent Child De, Abhishek Sarkar, Sumantra Sharma, Nidhi Ansari, Asad Reja, Abu Hena Hasanoor Sarda, Aarti Indian J Dermatol Case Report One 2-year-old undernourished girl presented to our outpatient with large erythematous scaly plaques in arm along with multiple bony swellings over nose, fingers, left foot, and back for the past 1 year. Apart from skin and bone lesions the girl was also had intermittent fever, pallor, irritability, and malnourishment. Her parents gave a history of incomplete healing at the BCG vaccination site. The case was diagnosed to be case of disseminated mycobacterial infection skin and bone with the help of histopathology, radiological examination, and DNA polymerase chain reaction (PCR). DNA PCR from the skin lesion came positive for mycobacteria tuberculosis complex. The girl was treated with 6 months of standard antitubercular drug treatment with very good improvement not only of her cutaneous and bone changes but also of her general health and growth. We report the case because paucity of similar infection in literature and for greater recognition of potential epidemiological threat. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5618842/ /pubmed/28979017 http://dx.doi.org/10.4103/ijd.IJD_55_17 Text en Copyright: © 2017 Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report De, Abhishek Sarkar, Sumantra Sharma, Nidhi Ansari, Asad Reja, Abu Hena Hasanoor Sarda, Aarti BCG-induced Disseminated Mycobacterial Infection of Skin and Bone in an Otherwise Immunocompetent Child |
title | BCG-induced Disseminated Mycobacterial Infection of Skin and Bone in an Otherwise Immunocompetent Child |
title_full | BCG-induced Disseminated Mycobacterial Infection of Skin and Bone in an Otherwise Immunocompetent Child |
title_fullStr | BCG-induced Disseminated Mycobacterial Infection of Skin and Bone in an Otherwise Immunocompetent Child |
title_full_unstemmed | BCG-induced Disseminated Mycobacterial Infection of Skin and Bone in an Otherwise Immunocompetent Child |
title_short | BCG-induced Disseminated Mycobacterial Infection of Skin and Bone in an Otherwise Immunocompetent Child |
title_sort | bcg-induced disseminated mycobacterial infection of skin and bone in an otherwise immunocompetent child |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618842/ https://www.ncbi.nlm.nih.gov/pubmed/28979017 http://dx.doi.org/10.4103/ijd.IJD_55_17 |
work_keys_str_mv | AT deabhishek bcginduceddisseminatedmycobacterialinfectionofskinandboneinanotherwiseimmunocompetentchild AT sarkarsumantra bcginduceddisseminatedmycobacterialinfectionofskinandboneinanotherwiseimmunocompetentchild AT sharmanidhi bcginduceddisseminatedmycobacterialinfectionofskinandboneinanotherwiseimmunocompetentchild AT ansariasad bcginduceddisseminatedmycobacterialinfectionofskinandboneinanotherwiseimmunocompetentchild AT rejaabuhenahasanoor bcginduceddisseminatedmycobacterialinfectionofskinandboneinanotherwiseimmunocompetentchild AT sardaaarti bcginduceddisseminatedmycobacterialinfectionofskinandboneinanotherwiseimmunocompetentchild |