Diffusion tensor imaging studies in vascular disease: A review of the literature

Cerebrovascular disease (CVD) is often present in old age and may be associated with microstructural pathology of white matter (WM) and cognitive dysfunction. The current review investigated the relationship between CVD, cognitive status and WM integrity as assessed by diffusion tensor imaging (DTI)...

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Autores principales: Alves, Gilberto Sousa, Sudo, Felipe Kenji, Alves, Carlos Eduardo de Oliveira, Ericeira-Valente, Letice, Moreira, Denise Madeira, Engelhardt, Eliasz, Laks, Jerson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Neurologia Cognitiva e do Comportamento 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618963/
https://www.ncbi.nlm.nih.gov/pubmed/29213790
http://dx.doi.org/10.1590/S1980-57642012DN06030008
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author Alves, Gilberto Sousa
Sudo, Felipe Kenji
Alves, Carlos Eduardo de Oliveira
Ericeira-Valente, Letice
Moreira, Denise Madeira
Engelhardt, Eliasz
Laks, Jerson
author_facet Alves, Gilberto Sousa
Sudo, Felipe Kenji
Alves, Carlos Eduardo de Oliveira
Ericeira-Valente, Letice
Moreira, Denise Madeira
Engelhardt, Eliasz
Laks, Jerson
author_sort Alves, Gilberto Sousa
collection PubMed
description Cerebrovascular disease (CVD) is often present in old age and may be associated with microstructural pathology of white matter (WM) and cognitive dysfunction. The current review investigated the relationship between CVD, cognitive status and WM integrity as assessed by diffusion tensor imaging (DTI). METHODS: DTI studies were searched on ISI and Pubmed databases from 2002 to 2012. RESULTS: Studies evidenced DTI changes in WM as associated with vascular disease and provide increasing support for DTI as a valuable method for early detection of CVD. CONCLUSION: DTI parameters can serve as important biomarkers in monitoring vascular disease progression and treatment response and may represent a surrogate marker of WM tract integrity.
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spelling pubmed-56189632017-12-06 Diffusion tensor imaging studies in vascular disease: A review of the literature Alves, Gilberto Sousa Sudo, Felipe Kenji Alves, Carlos Eduardo de Oliveira Ericeira-Valente, Letice Moreira, Denise Madeira Engelhardt, Eliasz Laks, Jerson Dement Neuropsychol Original Articles Cerebrovascular disease (CVD) is often present in old age and may be associated with microstructural pathology of white matter (WM) and cognitive dysfunction. The current review investigated the relationship between CVD, cognitive status and WM integrity as assessed by diffusion tensor imaging (DTI). METHODS: DTI studies were searched on ISI and Pubmed databases from 2002 to 2012. RESULTS: Studies evidenced DTI changes in WM as associated with vascular disease and provide increasing support for DTI as a valuable method for early detection of CVD. CONCLUSION: DTI parameters can serve as important biomarkers in monitoring vascular disease progression and treatment response and may represent a surrogate marker of WM tract integrity. Associação de Neurologia Cognitiva e do Comportamento 2012 /pmc/articles/PMC5618963/ /pubmed/29213790 http://dx.doi.org/10.1590/S1980-57642012DN06030008 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Alves, Gilberto Sousa
Sudo, Felipe Kenji
Alves, Carlos Eduardo de Oliveira
Ericeira-Valente, Letice
Moreira, Denise Madeira
Engelhardt, Eliasz
Laks, Jerson
Diffusion tensor imaging studies in vascular disease: A review of the literature
title Diffusion tensor imaging studies in vascular disease: A review of the literature
title_full Diffusion tensor imaging studies in vascular disease: A review of the literature
title_fullStr Diffusion tensor imaging studies in vascular disease: A review of the literature
title_full_unstemmed Diffusion tensor imaging studies in vascular disease: A review of the literature
title_short Diffusion tensor imaging studies in vascular disease: A review of the literature
title_sort diffusion tensor imaging studies in vascular disease: a review of the literature
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618963/
https://www.ncbi.nlm.nih.gov/pubmed/29213790
http://dx.doi.org/10.1590/S1980-57642012DN06030008
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