Vascular cognitive impairment in Pemphigus vulgaris: A case report

Pemphigus vulgaris is a systemic auto-immune medical condition that mainly manifests with changes in skin and vasculopathy. This is a case report of a 69-year-old male with confirmed histopathologic diagnosis of Pemphigus vulgaris presenting ulterior Cognitive Impairment, mostly in executive functio...

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Detalles Bibliográficos
Autores principales: Siqueira-Neto, José Ibiapina, Sales, Paulo Marcelo Gondim, Sobreira, Emmanuelle Silva Tavares, Limeira, Aline Miranda, Araujo, Heline Bessa, dos Santos, Júnia Vieira, de Castro, José Daniel Vieira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Neurologia Cognitiva e do Comportamento 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618969/
https://www.ncbi.nlm.nih.gov/pubmed/29213796
http://dx.doi.org/10.1590/S1980-57642012DN06030014
Descripción
Sumario:Pemphigus vulgaris is a systemic auto-immune medical condition that mainly manifests with changes in skin and vasculopathy. This is a case report of a 69-year-old male with confirmed histopathologic diagnosis of Pemphigus vulgaris presenting ulterior Cognitive Impairment, mostly in executive function. The patient was treated using steroids, immunomodulatory therapy, fluoxetine and galantamine. Neuropsychological testing and magnetic resonance (MRI) were performed. This is the first report of correlational cognitive impairment with Pemphigus vulgaris in the literature. Physicians should be aware of vascular causes for cognitive impairment in patients presenting auto-immune conditions.

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