Cargando…

Ldt(Mav2), a nonclassical transpeptidase and susceptibility of Mycobacterium avium to carbapenems

AIM: Mycobacterium avium infections, especially in immune-compromised individuals, present a significant challenge as therapeutic options are limited. In this study, we investigated if M. avium genome encodes nonclassical transpeptidases and if newer carbapenems are effective against this mycobacter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mattoo, Rohini, Lloyd, Evan P, Kaushik, Amit, Kumar, Pankaj, Brunelle, Julie L, Townsend, Craig A, Lamichhane, Gyanu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Medicine Ltd 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619143/ https://www.ncbi.nlm.nih.gov/pubmed/28555497 http://dx.doi.org/10.2217/fmb-2016-0208

Ejemplares similares

Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase Ldt(Mt2) by biapenem and tebipenem
por: Bianchet, Mario A., et al.
Publicado: (2017)

The Mycobacterium tuberculosis gene, ldt(Mt2), encodes a non-classical transpeptidase required for virulence and resistance to amoxicillin
por: Gupta, Radhika, et al.
Publicado: (2010)

Non-classical transpeptidases yield insight into new antibacterials
por: Kumar, Pankaj, et al.
Publicado: (2016)

Structure of Ldt(Mt2), an l,d-transpeptidase from Mycobacterium tuberculosis
por: Böth, Dominic, et al.
Publicado: (2013)

Targeting the Mycobacterium tuberculosis transpeptidase Ldt(Mt2) with cysteine-reactive inhibitors including ebselen
por: de Munnik, Mariska, et al.
Publicado: (2019)

A Fluorescence‐Based Assay for Screening β‐Lactams Targeting the Mycobacterium tuberculosis Transpeptidase Ldt(Mt2)
por: de Munnik, Mariska, et al.
Publicado: (2019)

High-throughput screen with the l,d-transpeptidase Ldt(Mt2) of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors
por: de Munnik, Mariska, et al.
Publicado: (2023)

Protective Efficacy of BCG Overexpressing an L,D-Transpeptidase against M. tuberculosis Infection
por: Nolan, Scott T., et al.
Publicado: (2010)

Assessment of carbapenems in a mouse model of Mycobacterium tuberculosis infection
por: Jadhav, Ravindra, et al.
Publicado: (2021)

Allosteric cooperation in β-lactam binding to a non-classical transpeptidase
por: Ahmad, Nazia, et al.
Publicado: (2022)

Virulence-related Mycobacterium avium subsp hominissuis MAV_2928 gene is associated with vacuole remodeling in macrophages
por: Jha, Samradhni S, et al.
Publicado: (2010)

Mycobacterium avium MAV2054 protein induces macrophage apoptosis by targeting mitochondria and reduces intracellular bacterial growth
por: Lee, Kang-In, et al.
Publicado: (2016)

Point mutation in the stop codon of MAV_RS14660 increases the growth rate of Mycobacterium avium subspecies hominissuis
por: Kawakita, Tomomi, et al.
Publicado: (2020)

MAV_4644 Interaction with the Host Cathepsin Z Protects Mycobacterium avium subsp. hominissuis from Rapid Macrophage Killing
por: Lewis, Matthew S., et al.
Publicado: (2019)

Mycobacterium Tuberculosis Response to Stress from Reactive Oxygen and Nitrogen Species
por: Lamichhane, Gyanu
Publicado: (2011)

Zinc is an inhibitor of the LdtR transcriptional activator
por: Pagliai, Fernando A., et al.
Publicado: (2018)

Penicillin Binding Proteins and β-Lactamases of Mycobacterium tuberculosis: Reexamination of the Historical Paradigm
por: Kumar, Gaurav, et al.
Publicado: (2022)

803. Overcoming β-Lactam Resistance in Mycobacterium abscessus
por: Story-Roller, Elizabeth, et al.
Publicado: (2018)

A comparative study of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuis in experimentally infected pigs
por: Agdestein, Angelika, et al.
Publicado: (2012)

Development of a penem antibiotic against Mycobacteroides abscessus
por: Batchelder, Hunter R., et al.
Publicado: (2020)

Genomic homogeneity between Mycobacterium avium subsp. avium and Mycobacterium avium subsp. paratuberculosis belies their divergent growth rates
por: Bannantine, John P, et al.
Publicado: (2003)

Isolation, Purification and Characterization of L,D-transpeptidase 2 from Mycobacterium tuberculosis
por: Baldin, S. M., et al.
Publicado: (2019)

Nonclassical Recrystallization
por: Brunner, Julian, et al.
Publicado: (2020)

LdtR is a master regulator of gene expression in Liberibacter asiaticus
por: Pagliai, Fernando A., et al.
Publicado: (2017)

A tale of two images: From mycobacterium avium complex-lung disease (MAC-LD) to mycobacterium avium complex-pleural disease()
por: Varkey, Mary Rithu, et al.
Publicado: (2021)

Identification of a Ligand Binding Pocket in LdtR from Liberibacter asiaticus
por: Pagliai, Fernando A., et al.
Publicado: (2015)

Diagnosis of Parkinson’s Disease by A Metabolomics-Based Laboratory-Developed Test (LDT)
por: Lokhov, Petr G., et al.
Publicado: (2020)

Consolidations in Nodular Bronchiectatic Mycobacterium Avium Complex Lung Disease: Mycobacterium Avium Complex or Other Infection?
por: Im, Soo Ah, et al.
Publicado: (2010)

Essential Metabolites of Mycobacterium tuberculosis and Their Mimics
por: Lamichhane, Gyanu, et al.
Publicado: (2011)

The MAVS and MAV-Nots: PINK1 Clears Prion-like MAVS Aggregates to Extinguish Mitochondrial Inflammatory Signaling
por: Rai, Prashant, et al.
Publicado: (2021)

Mycobacterium abscessus and β-Lactams: Emerging Insights and Potential Opportunities
por: Story-Roller, Elizabeth, et al.
Publicado: (2018)

Detection of Mycobacterium avium in pet birds
por: Godoy, Silvia Neri, et al.
Publicado: (2009)

Mannosylated Lipoarabinomannans from Mycobacterium Avium Subsp. Paratuberculosis Alters the Inflammatory Response by Bovine Macrophages and Suppresses Killing of Mycobacterium Avium Subsp. Avium Organisms
por: Souza, Cleverson, et al.
Publicado: (2013)

Complete Genome Sequence of Mycobacterium avium subsp. avium Chester (DSM 44156)
por: Goethe, Ralph, et al.
Publicado: (2020)

Increasing cellular lifespan with a flow system in organotypic culture of the Laterodorsal Tegmentum (LDT)
por: Romero-Leguizamón, César R., et al.
Publicado: (2019)

In vitro diagnostic medical device regulation (IVDR): the end of laboratory developed tests (LDT)?
por: Barberis, Massimo
Publicado: (2021)

Desiccation-Tolerance of Mycobacterium avium, Mycobacterium intracellulare, Mycobacterium chimaera, Mycobacterium abscessus and Mycobacterium chelonae
por: Falkinham, Joseph O., et al.
Publicado: (2022)

Theory of nonclassical states of light /
Publicado: (2003)

Nonclassical Vitamin D Action
por: Zittermann, Armin, et al.
Publicado: (2010)

Nonclassic Congenital Adrenal Hyperplasia
por: Witchel, Selma Feldman, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_pso171iv83i7in6137m66askd9