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Serum levels of soluble TNF-α receptors but not BDNF are associated with apathy symptoms in mild Alzheimer's disease and amnestic mild cognitive impairment

Apathy is intimately associated with dementia. Unfortunately, its pathophysiology remains poorly understood. The motivational impairment that characterizes this disorder might share the same inflammatory mechanisms, as suggested by the sickness behavior theory. OBJECTIVE: The primary aim of this stu...

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Detalles Bibliográficos
Autores principales: Guimarães, Henrique Cerqueira, Caramelli, Paulo, Fialho, Patricia Paes Araujo, França, Elisa de Paula, Afonso, Marcelo Pelizzaro Dias, Teixeira, Antonio Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Neurologia Cognitiva e do Comportamento 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619202/
https://www.ncbi.nlm.nih.gov/pubmed/29213854
http://dx.doi.org/10.1590/S1980-57642013DN70300011