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Screening for cognitive impairment in late onset depression in a Brazilian sample using the BBRC-Edu
Depression and dementia are the most prevalent neuropsychiatric disorders in the elderly population. Alzheimer's disease is the leading cause of dementia in most countries, being responsible for more than half of all dementia cases. Late-onset depression is a frequent cause of cognitive decline...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação de Neurologia Cognitiva e do
Comportamento
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619246/ https://www.ncbi.nlm.nih.gov/pubmed/29213779 http://dx.doi.org/10.1590/S1980-57642012DN06020004 |
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author | Novaretti, Tânia Maria da Silva Radanovic, Marcia Nitrini, Ricardo |
author_facet | Novaretti, Tânia Maria da Silva Radanovic, Marcia Nitrini, Ricardo |
author_sort | Novaretti, Tânia Maria da Silva |
collection | PubMed |
description | Depression and dementia are the most prevalent neuropsychiatric disorders in the elderly population. Alzheimer's disease is the leading cause of dementia in most countries, being responsible for more than half of all dementia cases. Late-onset depression is a frequent cause of cognitive decline in the elderly. Differentiating between cognitive impairment secondary to depression and incipient dementia poses a challenge in the clinical setting. OBJECTIVE: To evaluate the performance of elderly depressed patients using the BBRC-Edu. METHODS: We studied 25 patients with late onset depression (mean age: 73.6 y (6.6); schooling: 9.1 y (5.7)) and 30 patients with mild AD (mean age 76.6 y (5.4); schooling: 7.5 y (7.1)), who were compared to a control group of 30 healthy elderly (mean age 73.8 y (5.8); schooling: 9.1 y (5.4)) using the CERAD and BBRC-Edu batteries. RESULTS: For the CERAD battery, depressed patients performed better than AD patients on all tasks (p<0.0001) except for Constructional Praxis (p>0.05), and performed poorer than controls on verbal fluency (animals) and Word List Recall tasks (p<0.0001). For the BBRC-Edu, depressed patients performed better than AD patients on all tasks (p<0.0001) except for Digit Span (direct order) (p=0.076) and Incidental Memory (p>0.05), and performed worse than controls on Learning (second presentation) and verbal fluency (fruits) tasks (p<0.0001). CONCLUSION: Overall performance on the BBRC-Edu allowed differentiation of controls and depressed patients from AD patients. |
format | Online Article Text |
id | pubmed-5619246 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Associação de Neurologia Cognitiva e do
Comportamento |
record_format | MEDLINE/PubMed |
spelling | pubmed-56192462017-12-06 Screening for cognitive impairment in late onset depression in a Brazilian sample using the BBRC-Edu Novaretti, Tânia Maria da Silva Radanovic, Marcia Nitrini, Ricardo Dement Neuropsychol Original Articles Depression and dementia are the most prevalent neuropsychiatric disorders in the elderly population. Alzheimer's disease is the leading cause of dementia in most countries, being responsible for more than half of all dementia cases. Late-onset depression is a frequent cause of cognitive decline in the elderly. Differentiating between cognitive impairment secondary to depression and incipient dementia poses a challenge in the clinical setting. OBJECTIVE: To evaluate the performance of elderly depressed patients using the BBRC-Edu. METHODS: We studied 25 patients with late onset depression (mean age: 73.6 y (6.6); schooling: 9.1 y (5.7)) and 30 patients with mild AD (mean age 76.6 y (5.4); schooling: 7.5 y (7.1)), who were compared to a control group of 30 healthy elderly (mean age 73.8 y (5.8); schooling: 9.1 y (5.4)) using the CERAD and BBRC-Edu batteries. RESULTS: For the CERAD battery, depressed patients performed better than AD patients on all tasks (p<0.0001) except for Constructional Praxis (p>0.05), and performed poorer than controls on verbal fluency (animals) and Word List Recall tasks (p<0.0001). For the BBRC-Edu, depressed patients performed better than AD patients on all tasks (p<0.0001) except for Digit Span (direct order) (p=0.076) and Incidental Memory (p>0.05), and performed worse than controls on Learning (second presentation) and verbal fluency (fruits) tasks (p<0.0001). CONCLUSION: Overall performance on the BBRC-Edu allowed differentiation of controls and depressed patients from AD patients. Associação de Neurologia Cognitiva e do Comportamento 2012 /pmc/articles/PMC5619246/ /pubmed/29213779 http://dx.doi.org/10.1590/S1980-57642012DN06020004 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Novaretti, Tânia Maria da Silva Radanovic, Marcia Nitrini, Ricardo Screening for cognitive impairment in late onset depression in a Brazilian sample using the BBRC-Edu |
title | Screening for cognitive impairment in late onset depression in a
Brazilian sample using the BBRC-Edu |
title_full | Screening for cognitive impairment in late onset depression in a
Brazilian sample using the BBRC-Edu |
title_fullStr | Screening for cognitive impairment in late onset depression in a
Brazilian sample using the BBRC-Edu |
title_full_unstemmed | Screening for cognitive impairment in late onset depression in a
Brazilian sample using the BBRC-Edu |
title_short | Screening for cognitive impairment in late onset depression in a
Brazilian sample using the BBRC-Edu |
title_sort | screening for cognitive impairment in late onset depression in a
brazilian sample using the bbrc-edu |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619246/ https://www.ncbi.nlm.nih.gov/pubmed/29213779 http://dx.doi.org/10.1590/S1980-57642012DN06020004 |
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