Dementia in motor neuron disease: Reviewing the role of MRI in diagnosis

The superimposed clinical features of motor neuron disease (MND) and frontotemporal dementia (FTD) comprise a distinct, yet not fully understood, neurological overlap syndrome whose clinicopathological basis has recently been reviewed. Here, we present a review of the clinical, pathological and gene...

Descripción completa

Detalles Bibliográficos
Autores principales: da Rocha, Antonio José, Nunes, Renato Hoffmann, Maia Jr., Antonio Carlos Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Neurologia Cognitiva e do Comportamento 2015
Materias:
Views & Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619319/
https://www.ncbi.nlm.nih.gov/pubmed/29213986
http://dx.doi.org/10.1590/1980-57642015DN94000369
Descripción
Sumario:The superimposed clinical features of motor neuron disease (MND) and frontotemporal dementia (FTD) comprise a distinct, yet not fully understood, neurological overlap syndrome whose clinicopathological basis has recently been reviewed. Here, we present a review of the clinical, pathological and genetic basis of MND-FTD and the role of MRI in its diagnosis. In doing so, we discuss current techniques that depict the involvement of the selective corticospinal tract (CST) and temporal lobe in MND-FTD.

Ejemplares similares