Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings

A 35-year-old, previously healthy man presented psychiatric symptoms lasting four years, receiving treatment with neuroleptics. One year later he evolved with gait disequilibrium. After a further six months, cognitive symptoms were characterized with rapid evolution to a profound demented state. MRI...

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Autores principales: Galvão, Antonio Cézar Ribeiro, Machado-Porto, Gislaine Cristina Lopes, Porto, Fábio Henrique de Gobbi, Lucato, Leandro Tavares, Nitrini, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Neurologia Cognitiva e do Comportamento 2012
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619343/
https://www.ncbi.nlm.nih.gov/pubmed/29213811
http://dx.doi.org/10.1590/S1980-57642012DN06040015
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author Galvão, Antonio Cézar Ribeiro
Machado-Porto, Gislaine Cristina Lopes
Porto, Fábio Henrique de Gobbi
Lucato, Leandro Tavares
Nitrini, Ricardo
author_facet Galvão, Antonio Cézar Ribeiro
Machado-Porto, Gislaine Cristina Lopes
Porto, Fábio Henrique de Gobbi
Lucato, Leandro Tavares
Nitrini, Ricardo
author_sort Galvão, Antonio Cézar Ribeiro
collection PubMed
description A 35-year-old, previously healthy man presented psychiatric symptoms lasting four years, receiving treatment with neuroleptics. One year later he evolved with gait disequilibrium. After a further six months, cognitive symptoms were characterized with rapid evolution to a profound demented state. MRI showed signal changes in cerebral white matter and very long-chain fatty acids were detected in blood.
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spelling pubmed-56193432017-12-06 Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings Galvão, Antonio Cézar Ribeiro Machado-Porto, Gislaine Cristina Lopes Porto, Fábio Henrique de Gobbi Lucato, Leandro Tavares Nitrini, Ricardo Dement Neuropsychol Case Reports A 35-year-old, previously healthy man presented psychiatric symptoms lasting four years, receiving treatment with neuroleptics. One year later he evolved with gait disequilibrium. After a further six months, cognitive symptoms were characterized with rapid evolution to a profound demented state. MRI showed signal changes in cerebral white matter and very long-chain fatty acids were detected in blood. Associação de Neurologia Cognitiva e do Comportamento 2012 /pmc/articles/PMC5619343/ /pubmed/29213811 http://dx.doi.org/10.1590/S1980-57642012DN06040015 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Galvão, Antonio Cézar Ribeiro
Machado-Porto, Gislaine Cristina Lopes
Porto, Fábio Henrique de Gobbi
Lucato, Leandro Tavares
Nitrini, Ricardo
Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings
title Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings
title_full Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings
title_fullStr Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings
title_full_unstemmed Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings
title_short Adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: MRI findings
title_sort adult-onset adrenoleukodystrophy presenting as a psychiatric disorder: mri findings
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619343/
https://www.ncbi.nlm.nih.gov/pubmed/29213811
http://dx.doi.org/10.1590/S1980-57642012DN06040015
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