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Neuroprotective actions of 2,4-dinitrophenol: Friend or foe?

2,4-dinitrophenol (DNP) has long been known to be toxic at high concentrations, an effect related to uncoupling of mitochondrial oxidative phosphorylation. Five years ago, however, we reported that low concentrations of DNP protect neurons against the toxicity of the amyloid-β peptide. Since then, a...

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Detalles Bibliográficos
Autores principales: Ferreira, Sérgio Teixeira, Felice, Fernanda Guarino De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Neurologia Cognitiva e do Comportamento 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619426/
https://www.ncbi.nlm.nih.gov/pubmed/29213408
http://dx.doi.org/10.1590/S1980-57642008DN10400002