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Identification of breast cancer associated variants that modulate transcription factor binding
Genome-wide association studies (GWAS) have discovered thousands loci associated with disease risk and quantitative traits, yet most of the variants responsible for risk remain uncharacterized. The majority of GWAS-identified loci are enriched for non-coding single-nucleotide polymorphisms (SNPs) an...
Autores principales: | Liu, Yunxian, Walavalkar, Ninad M., Dozmorov, Mikhail G., Rich, Stephen S., Civelek, Mete, Guertin, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619690/ https://www.ncbi.nlm.nih.gov/pubmed/28957321 http://dx.doi.org/10.1371/journal.pgen.1006761 |
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