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Gestational hypoxia disrupts the neonatal leptin surge and programs hyperphagia and obesity in male offspring in the Sprague-Dawley rat

The effect of gestational hypoxia on the neonatal leptin surge, development of hypothalamic arcuate nuclei (ARH) projections and appetite that could contribute to the programming of offspring obesity is lacking. We examined the effect of 12% O(2) from gestational days 15–19 in the Sprague-Dawley rat...

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Detalles Bibliográficos
Autores principales:	Vargas, Vladimir E., Gurung, Sunam, Grant, Benjamin, Hyatt, Kimberly, Singleton, Krista, Myers, Sarah M., Saunders, Debra, Njoku, Charity, Towner, Rheal, Myers, Dean A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619766/ https://www.ncbi.nlm.nih.gov/pubmed/28957383 http://dx.doi.org/10.1371/journal.pone.0185272

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