Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis

Monocytes are innate immune cells that play a pivotal role in antifungal immunity, but little is known regarding the cellular metabolic events that regulate their function during infection. Using complementary transcriptomic and immunological studies in human primary monocytes, we show that activati...

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Detalles Bibliográficos
Autores principales: Domínguez-Andrés, Jorge, Arts, Rob J. W., ter Horst, Rob, Gresnigt, Mark S., Smeekens, Sanne P., Ratter, Jacqueline M., Lachmandas, Ekta, Boutens, Lily, van de Veerdonk, Frank L., Joosten, Leo A. B., Notebaart, Richard A., Ardavín, Carlos, Netea, Mihai G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619837/
https://www.ncbi.nlm.nih.gov/pubmed/28922415
http://dx.doi.org/10.1371/journal.ppat.1006632

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