A DNA vaccine for Crimean-Congo hemorrhagic fever protects against disease and death in two lethal mouse models

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus capable of causing a severe hemorrhagic fever disease in humans. There are currently no licensed vaccines to prevent CCHFV-associated disease. We developed a DNA vaccine expressing the M-segment glycoprotein precursor gene of CCHFV...

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Detalles Bibliográficos
Autores principales: Garrison, Aura R., Shoemaker, Charles J., Golden, Joseph W., Fitzpatrick, Collin J., Suschak, John J., Richards, Michelle J., Badger, Catherine V., Six, Carolyn M., Martin, Jacqueline D., Hannaman, Drew, Zivcec, Marko, Bergeron, Eric, Koehler, Jeffrey W., Schmaljohn, Connie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619839/
https://www.ncbi.nlm.nih.gov/pubmed/28922426
http://dx.doi.org/10.1371/journal.pntd.0005908

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