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Declines in Malaria Burden and All-Cause Child Mortality following Increases in Control Interventions in Senegal, 2005–2010
Malaria is endemic in Senegal. The national malaria control strategy focuses on achieving universal coverage for major interventions, with a goal of reaching preelimination status by 2018. Senegal began distribution of insecticide-treated nets (ITNs) and introduced artemisinin-based combination ther...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Tropical Medicine and Hygiene
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619933/ https://www.ncbi.nlm.nih.gov/pubmed/28990913 http://dx.doi.org/10.4269/ajtmh.16-0953 |
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author | Thwing, Julie Eckert, Erin Dione, Demba Anta Tine, Roger Faye, Adama Yé, Yazoume Ndiop, Medoune Cisse, Moustapha Ndione, Jacques Andre Diouf, Mame Birame Ba, Mady |
author_facet | Thwing, Julie Eckert, Erin Dione, Demba Anta Tine, Roger Faye, Adama Yé, Yazoume Ndiop, Medoune Cisse, Moustapha Ndione, Jacques Andre Diouf, Mame Birame Ba, Mady |
author_sort | Thwing, Julie |
collection | PubMed |
description | Malaria is endemic in Senegal. The national malaria control strategy focuses on achieving universal coverage for major interventions, with a goal of reaching preelimination status by 2018. Senegal began distribution of insecticide-treated nets (ITNs) and introduced artemisinin-based combination therapy in 2006, then introduced rapid diagnostic tests in 2007. We evaluated the impact of these efforts using a plausibility design based on malaria’s contribution to all-cause under-five mortality (ACCM) and considering other contextual factors which may influence ACCM. Between 2005 and 2010, household ownership of ITNs increased from 20% to 63%, and the proportion of people sleeping under an ITN the night prior to the survey increased from 6% to 29%. Malaria parasite prevalence declined from 6% to 3% from 2008 to 2010 among children under five. Some nonmalaria indicators of child health improved, for example, increase of complete vaccination coverage from 58% to 64%; however, nutritional indicators deteriorated, with an increase in stunting from 16% to 26%. Although economic indicators improved, environmental conditions favored an increase in malaria transmission. ACCM decreased 40% between 2005 and 2010, from 121 (95% confidence interval [CI] 113–129) to 72 (95% CI 66–77) per 1,000, and declines were greater among age groups, epidemiologic zones, and wealth quintiles most at risk for malaria. After considering coverage of malaria interventions, trends in malaria morbidity, effects of contextual factors, and trends in ACCM, it is plausible that malaria control interventions contributed to a reduction in malaria mortality and to the impressive gains in child survival in Senegal. |
format | Online Article Text |
id | pubmed-5619933 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The American Society of Tropical Medicine and Hygiene |
record_format | MEDLINE/PubMed |
spelling | pubmed-56199332018-04-30 Declines in Malaria Burden and All-Cause Child Mortality following Increases in Control Interventions in Senegal, 2005–2010 Thwing, Julie Eckert, Erin Dione, Demba Anta Tine, Roger Faye, Adama Yé, Yazoume Ndiop, Medoune Cisse, Moustapha Ndione, Jacques Andre Diouf, Mame Birame Ba, Mady Am J Trop Med Hyg Articles Malaria is endemic in Senegal. The national malaria control strategy focuses on achieving universal coverage for major interventions, with a goal of reaching preelimination status by 2018. Senegal began distribution of insecticide-treated nets (ITNs) and introduced artemisinin-based combination therapy in 2006, then introduced rapid diagnostic tests in 2007. We evaluated the impact of these efforts using a plausibility design based on malaria’s contribution to all-cause under-five mortality (ACCM) and considering other contextual factors which may influence ACCM. Between 2005 and 2010, household ownership of ITNs increased from 20% to 63%, and the proportion of people sleeping under an ITN the night prior to the survey increased from 6% to 29%. Malaria parasite prevalence declined from 6% to 3% from 2008 to 2010 among children under five. Some nonmalaria indicators of child health improved, for example, increase of complete vaccination coverage from 58% to 64%; however, nutritional indicators deteriorated, with an increase in stunting from 16% to 26%. Although economic indicators improved, environmental conditions favored an increase in malaria transmission. ACCM decreased 40% between 2005 and 2010, from 121 (95% confidence interval [CI] 113–129) to 72 (95% CI 66–77) per 1,000, and declines were greater among age groups, epidemiologic zones, and wealth quintiles most at risk for malaria. After considering coverage of malaria interventions, trends in malaria morbidity, effects of contextual factors, and trends in ACCM, it is plausible that malaria control interventions contributed to a reduction in malaria mortality and to the impressive gains in child survival in Senegal. The American Society of Tropical Medicine and Hygiene 2017-09-27 /pmc/articles/PMC5619933/ /pubmed/28990913 http://dx.doi.org/10.4269/ajtmh.16-0953 Text en © The American Society of Tropical Medicine and Hygiene This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Articles Thwing, Julie Eckert, Erin Dione, Demba Anta Tine, Roger Faye, Adama Yé, Yazoume Ndiop, Medoune Cisse, Moustapha Ndione, Jacques Andre Diouf, Mame Birame Ba, Mady Declines in Malaria Burden and All-Cause Child Mortality following Increases in Control Interventions in Senegal, 2005–2010 |
title | Declines in Malaria Burden and All-Cause Child Mortality following Increases in Control Interventions in Senegal, 2005–2010 |
title_full | Declines in Malaria Burden and All-Cause Child Mortality following Increases in Control Interventions in Senegal, 2005–2010 |
title_fullStr | Declines in Malaria Burden and All-Cause Child Mortality following Increases in Control Interventions in Senegal, 2005–2010 |
title_full_unstemmed | Declines in Malaria Burden and All-Cause Child Mortality following Increases in Control Interventions in Senegal, 2005–2010 |
title_short | Declines in Malaria Burden and All-Cause Child Mortality following Increases in Control Interventions in Senegal, 2005–2010 |
title_sort | declines in malaria burden and all-cause child mortality following increases in control interventions in senegal, 2005–2010 |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5619933/ https://www.ncbi.nlm.nih.gov/pubmed/28990913 http://dx.doi.org/10.4269/ajtmh.16-0953 |
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