Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures

We have developed 3D-tumoroids and tumor slice in vitro culture systems from surgical tumor specimens derived from patients with colorectal cancer (CRC) or lung cancer to evaluate immune cell populations infiltrating cultured tissues. The system incorporates patient's peripherally and tumor-der...

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Detalles Bibliográficos
Autores principales: Finnberg, Niklas K., Gokare, Prashanth, Lev, Avital, Grivennikov, Sergei I., MacFarlane, Alexander W., Campbell, Kerry S., Winters, Ryan M., Kaputa, Karen, Farma, Jeffrey M., Abbas, Abbas El-Sayed, Grasso, Luigi, Nicolaides, Nicholas C., El-Deiry, Wafik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620133/
https://www.ncbi.nlm.nih.gov/pubmed/28977993
http://dx.doi.org/10.18632/oncotarget.19965

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