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Microtubule inhibitor, SP-6-27 inhibits angiogenesis and induces apoptosis in ovarian cancer cells

In ovarian cancer (OVCA), treatment failure due to chemo-resistance is a serious challenge. It is therefore critical to identify new therapies that are effective against resistant tumors and have reduced side effects. We recently identified 4-H-chromenes as tubulin depolymerizing agents that bind to...

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Detalles Bibliográficos
Autores principales: Kulshrestha, Arpita, Katara, Gajendra K., Ibrahim, Safaa A., Patil, Renukadevi, Patil, Shivaputra A., Beaman, Kenneth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620153/
https://www.ncbi.nlm.nih.gov/pubmed/28978013
http://dx.doi.org/10.18632/oncotarget.17549