Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death

Extracellular ATP (eATP) accumulation within the tumor microenvironment (TME) has the potential to activate purinergic signaling. The eATP evoked signaling effects bolster antitumor immune responses while exerting direct cytotoxicity on tumor cells and vascular endothelial cells, mediated at least i...

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Detalles Bibliográficos
Autores principales: de Andrade Mello, Paola, Bian, Shu, Savio, Luiz Eduardo Baggio, Zhang, Haohai, Zhang, Jingping, Junger, Wolfgang, Wink, Márcia Rosângela, Lenz, Guido, Buffon, Andréia, Wu, Yan, Robson, Simon Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620171/
https://www.ncbi.nlm.nih.gov/pubmed/28978031
http://dx.doi.org/10.18632/oncotarget.18595

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