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Celastrol ameliorates inflammation through inhibition of NLRP3 inflammasome activation

Celastrol exhibits potential anti-inflammatory activity in a variety of inflammatory diseases, but the mechanism remains poorly understood. Activation of NLRP3 inflammasome is involved in multiple inflammatory diseases. Here, we show that celastrol abolishes the NLRP3 inflammasome activation, inhibi...

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Detalles Bibliográficos
Autores principales:	Yu, Xianjun, Zhao, Qun, Zhang, Xixi, Zhang, Haiwei, Liu, Yongbo, Wu, Xiaoxia, Li, Ming, Li, Xiaoming, Zhang, Jingxuan, Ruan, Xuzhi, Zhang, Haibing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620174/ https://www.ncbi.nlm.nih.gov/pubmed/28978034 http://dx.doi.org/10.18632/oncotarget.18619

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