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Mitoriboscins: Mitochondrial-based therapeutics targeting cancer stem cells (CSCs), bacteria and pathogenic yeast
The “endo-symbiotic theory of mitochondrial evolution” states that mitochondrial organelles evolved from engulfed aerobic bacteria, after millions of years of symbiosis and adaptation. Here, we have exploited this premise to design new antibiotics and novel anti-cancer therapies, using a convergent...
Autores principales: | Ozsvari, Bela, Fiorillo, Marco, Bonuccelli, Gloria, Cappello, Anna Rita, Frattaruolo, Luca, Sotgia, Federica, Trowbridge, Rachel, Foster, Richard, Lisanti, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620185/ https://www.ncbi.nlm.nih.gov/pubmed/28978045 http://dx.doi.org/10.18632/oncotarget.19084 |
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