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Heparin antagonizes cisplatin resistance of A2780 ovarian cancer cells by affecting the Wnt signaling pathway

Low molecular weight heparin (LMWH), the guideline based drug for prophylaxis and treatment of cancer-associated thrombosis, was recently shown to sensitize cisplatin resistant A2780cis human ovarian cancer cells for cisplatin cytotoxicity upon 24 h pretreatment with 50 μg × mL(−1) of the LMWH tinza...

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Detalles Bibliográficos
Autores principales: Pfankuchen, Daniel Bastian, Baltes, Fabian, Batool, Tahira, Li, Jin-Ping, Schlesinger, Martin, Bendas, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620193/
https://www.ncbi.nlm.nih.gov/pubmed/28978053
http://dx.doi.org/10.18632/oncotarget.18738