Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux

Carboxypeptidase E (CPE) has recently been described as a multifunctional protein that regulates proliferation, migration and survival in several tumor entities. In glioblastoma (GBM), the most malignant primary brain tumor, secreted CPE (sCPE) was shown to modulate tumor cell migration. In our curr...

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Detalles Bibliográficos
Autores principales: Ilina, Elena I., Armento, Angela, Sanchez, Leticia Garea, Reichlmeir, Marina, Braun, Yannick, Penski, Cornelia, Capper, David, Sahm, Felix, Jennewein, Lukas, Harter, Patrick N., Zukunft, Sven, Fleming, Ingrid, Schulte, Dorothea, Le Guerroué, Francois, Behrends, Christian, Ronellenfitsch, Michael W., Naumann, Ulrike, Mittelbronn, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620194/
https://www.ncbi.nlm.nih.gov/pubmed/28978054
http://dx.doi.org/10.18632/oncotarget.18747

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