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MiR-200c inhibits bladder cancer progression by targeting lactate dehydrogenase A

Lactate dehydrogenase A (LDHA) is overexpressed in various cancers. We investigated LDHA expression and function in bladder cancer. We demonstrate that LDHA is up-regulated in bladder cancer cells and promotes proliferation, invasion, and glycolysis. Additionally, we found that microRNA (miR)-200c d...

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Detalles Bibliográficos
Autores principales: Yuan, Daozhang, Zheng, Shunsheng, Wang, Liyan, Li, Jing, Yang, Jianan, Wang, Bin, Chen, Xiong, Zhang, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620201/
https://www.ncbi.nlm.nih.gov/pubmed/28978061
http://dx.doi.org/10.18632/oncotarget.18801

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