Cargando…
MiR-200c inhibits bladder cancer progression by targeting lactate dehydrogenase A
Lactate dehydrogenase A (LDHA) is overexpressed in various cancers. We investigated LDHA expression and function in bladder cancer. We demonstrate that LDHA is up-regulated in bladder cancer cells and promotes proliferation, invasion, and glycolysis. Additionally, we found that microRNA (miR)-200c d...
Autores principales: | Yuan, Daozhang, Zheng, Shunsheng, Wang, Liyan, Li, Jing, Yang, Jianan, Wang, Bin, Chen, Xiong, Zhang, Xiaobo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620201/ https://www.ncbi.nlm.nih.gov/pubmed/28978061 http://dx.doi.org/10.18632/oncotarget.18801 |
Ejemplares similares
-
The Downregulation of miR-200c Promotes Lactate Dehydrogenase A Expression and Non-Small Cell Lung Cancer Progression
por: Lei, Wei, et al.
Publicado: (2018) -
miR-200b is a key regulator of tumor progression and metabolism targeting lactate dehydrogenase A in human malignant glioma
por: Hu, Su, et al.
Publicado: (2016) -
MiR-34b-3 and miR-449a inhibit malignant progression of nasopharyngeal carcinoma by targeting lactate dehydrogenase A
por: Li, Huiling, et al.
Publicado: (2016) -
Thyrotroph embryonic factor is downregulated in bladder cancer and suppresses proliferation and tumorigenesis via the AKT/FOXOs signalling pathway
por: Yang, Jianan, et al.
Publicado: (2018) -
miR-200b and miR-200c co-contribute to the cisplatin sensitivity of ovarian cancer cells by targeting DNA methyltransferases
por: Liu, Jue, et al.
Publicado: (2019)