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Cross-talk between p21-activated kinase 4 and ERα signaling triggers endometrial cancer cell proliferation
Cross-talk between estrogen receptor alpha (ERα) and signal transduction pathways plays an important role in the progression of endometrial cancer (EC). Here, we show that 17β-estradiol (E(2)) stimulation increases p21-activated kinase 4 (Pak4) expression and activation in ER-positive EC cells. The...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620238/ https://www.ncbi.nlm.nih.gov/pubmed/28978098 http://dx.doi.org/10.18632/oncotarget.19188 |