Cargando…

Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells

Induction of necroptosis has emerged as an alternative approach to trigger programmed cell death, in particular in apoptosis-resistant cancer cells. Recent evidence suggests that kinase inhibitors targeting oncogenic B-RAF can also affect Receptor-interacting serine/threonine-protein kinase (RIP)1 a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feldmann, Friederike, Schenk, Barbara, Martens, Sofie, Vandenabeele, Peter, Fulda, Simone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620249/ https://www.ncbi.nlm.nih.gov/pubmed/28978109 http://dx.doi.org/10.18632/oncotarget.19919

Ejemplares similares

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury
por: Martens, Sofie, et al.
Publicado: (2017)

Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells
por: Alharbi, Raed A., et al.
Publicado: (2017)

Sorafenib-induced defective autophagy promotes cell death by necroptosis
por: Kharaziha, Pedram, et al.
Publicado: (2015)

Vitamin C controls neuronal necroptosis under oxidative stress
por: Ferrada, Luciano, et al.
Publicado: (2019)

Role of drug transporters in the sensitivity of acute myeloid leukemia to sorafenib
por: Macias, Rocio I.R., et al.
Publicado: (2018)

Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis
por: Steinhart, L, et al.
Publicado: (2013)

Exploiting Necroptosis for Therapy of Acute Lymphoblastic Leukemia
por: Mezzatesta, Caterina, et al.
Publicado: (2019)

HSP90α Mediates Sorafenib Resistance in Human Hepatocellular Carcinoma by Necroptosis Inhibition under Hypoxia
por: Liao, Yan, et al.
Publicado: (2021)

Molecular crosstalk between apoptosis, necroptosis, and survival signaling
por: Vanden Berghe, Tom, et al.
Publicado: (2015)

Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis
por: Weber, Kathrin, et al.
Publicado: (2018)

Overexpression of MFN2 alleviates sorafenib-induced cardiomyocyte necroptosis via the MAM-CaMKIIδ pathway in vitro and in vivo
por: Song, Ziping, et al.
Publicado: (2022)

Necrostatin-1 and necroptosis inhibition: Pathophysiology and therapeutic implications
por: Cao, Liyuan, et al.
Publicado: (2021)

Necroptosis in Immuno-Oncology and Cancer Immunotherapy
por: Sprooten, Jenny, et al.
Publicado: (2020)

The ALK inhibitor AZD3463 effectively inhibits growth of sorafenib-resistant acute myeloid leukemia
por: Moharram, Sausan A., et al.
Publicado: (2019)

Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice
por: He, Gui-Wei, et al.
Publicado: (2017)

Phenytoin inhibits necroptosis
por: von Mässenhausen, Anne, et al.
Publicado: (2018)

Characterizing the prognostic and therapeutic value of necroptosis in sarcoma based on necroptosis subtypes
por: Ma, Yibo, et al.
Publicado: (2022)

Sorafenib inhibited cell growth through the MEK/ERK signaling pathway in acute promyelocytic leukemia cells
por: Zhang, Yunjie, et al.
Publicado: (2018)

Correction: The ALK inhibitor AZD3463 effectively inhibits growth of sorafenib-resistant acute myeloid leukemia
por: Moharram, Sausan A., et al.
Publicado: (2019)

Induction Mechanism of Ferroptosis, Necroptosis, and Pyroptosis: A Novel Therapeutic Target in Nervous System Diseases
por: Tang, Lu, et al.
Publicado: (2023)

Melatonin enhances sorafenib-induced cytotoxicity in FLT3-ITD acute myeloid leukemia cells by redox modification
por: Tian, Tian, et al.
Publicado: (2019)

Redox Modulation and Induction of Ferroptosis as a New Therapeutic Strategy in Hepatocellular Carcinoma
por: Lippmann, Jana, et al.
Publicado: (2020)

Necroptosis as a potential therapeutic target in multiple organ dysfunction syndrome
por: Cui, Yao-Li, et al.
Publicado: (2017)

A pharmacodynamic study of sorafenib in patients with relapsed and refractory acute leukemias
por: Pratz, Keith W., et al.
Publicado: (2010)

Bypassing drug resistance by triggering necroptosis: recent advances in mechanisms and its therapeutic exploitation in leukemia
por: Huang, Xianbo, et al.
Publicado: (2018)

Correction to: Phenytoin inhibits necroptosis
por: von Mässenhausen, Anne, et al.
Publicado: (2018)

Optogenetic Induction of Pyroptosis, Necroptosis, and Apoptosis in Mammalian Cell Lines
por: Shkarina, Kateryna, et al.
Publicado: (2023)

Venetoclax Overcomes Sorafenib Resistance in Acute Myeloid Leukemia by Targeting BCL2
por: Xu, Xi, et al.
Publicado: (2023)

Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation
por: Devos, Michael, et al.
Publicado: (2020)

Triple Akt inhibition as a new therapeutic strategy in T-cell acute lymphoblastic leukemia
por: Cani, Alice, et al.
Publicado: (2015)

Smac mimetics and TRAIL cooperate to induce MLKL-dependent necroptosis in Burkitt's lymphoma cell lines
por: Koch, Annkathrin, et al.
Publicado: (2021)

Induction treatments for acute promyelocytic leukemia: a network meta-analysis
por: Huang, Junjie, et al.
Publicado: (2016)

Angiopoietin 2 Is Associated with Vascular Necroptosis Induction in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome
por: Price, David R., et al.
Publicado: (2022)

Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells
por: Saveljeva, S, et al.
Publicado: (2015)

Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis
por: Nicolai, S, et al.
Publicado: (2015)

Sorafenib Dose Recommendation in Acute Myeloid Leukemia Based on Exposure‐FLT3 Relationship
por: Liu, Tao, et al.
Publicado: (2018)

Characteristic ERK1/2 signaling dynamics distinguishes necroptosis from apoptosis
por: Sipieter, François, et al.
Publicado: (2021)

USP22 controls necroptosis by regulating receptor‐interacting protein kinase 3 ubiquitination
por: Roedig, Jens, et al.
Publicado: (2020)

Sorafenib inhibits macrophage-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
por: Deng, Yan-Ru, et al.
Publicado: (2016)

Targeted inhibition of ACLY expression to reverse the resistance of sorafenib in hepatocellular carcinoma
por: Sun, Hong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nb0qkusbfm61ub38nie4hqogut