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Regorafenib in combination with silybin as a novel potential strategy for the treatment of metastatic colorectal cancer
PURPOSE: Regorafenib, an oral multikinase inhibitor, has demonstrated survival benefit in metastatic colorectal cancer (mCRC) patients that have progressed after all standard therapies. However, novel strategies to improve tolerability and enhance anti-cancer efficacy are needed. EXPERIMENTAL DESIGN...
Autores principales: | Belli, Valentina, Sforza, Vincenzo, Cardone, Claudia, Martinelli, Erika, Barra, Giusi, Matrone, Nunzia, Napolitano, Stefania, Morgillo, Floriana, Tuccillo, Concetta, Federico, Alessandro, Dallio, Marcello, Loguercio, Carmelina, Gravina, Antonietta Gerarda, Palma, Raffaele De, Ciardiello, Fortunato, Troiani, Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620258/ https://www.ncbi.nlm.nih.gov/pubmed/28978118 http://dx.doi.org/10.18632/oncotarget.20054 |
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