Targeting the PI3K/AKT/mTOR signaling pathway as an effectively radiosensitizing strategy for treating human oral squamous cell carcinoma in vitro and in vivo

Radiation therapy (RT) is the current standard adjuvant approach for oral squamous cell carcinoma (OSCC) patients. Radioresistance is a major contributor to radiotherapy failure. In this study, we used patient-derived cells and a radiation-resistant cell line in vitro and in vivo for two purposes: e...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Chih-Chia, Hung, Shih-Kai, Lin, Hon-Yi, Chiou, Wen-Yen, Lee, Moon-Sing, Liao, Hui-Fen, Huang, Hsien-Bin, Ho, Hsu-Chueh, Su, Yu-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620284/
https://www.ncbi.nlm.nih.gov/pubmed/28978144
http://dx.doi.org/10.18632/oncotarget.19817

Ejemplares similares

Ejemplares similares