Novel SOX17 frameshift mutations in endometrial cancer are functionally distinct from recurrent missense mutations

Extensive genomic profiling for endometrioid endometrial carcinoma (EEC) has pointed to genes and pathways important in uterine development as critical mediators of endometrial tumorigenesis. SOX17 is a developmental transcription factor necessary for proper endoderm formation that has been implicat...

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Detalles Bibliográficos
Autores principales: Walker, Christopher J., O'Hern, Matthew J., Serna, Vanida A., Kurita, Takeshi, Miranda, Mario A., Sapp, Caroline E., Mutch, David G., Cohn, David E., Goodfellow, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620294/
https://www.ncbi.nlm.nih.gov/pubmed/28978154
http://dx.doi.org/10.18632/oncotarget.20213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620294/
https://www.ncbi.nlm.nih.gov/pubmed/28978154
http://dx.doi.org/10.18632/oncotarget.20213

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