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Experience collecting interim data on mortality: an example from the RALES study
INTRODUCTION: The Randomized Aldactone Evaluation Study (RALES) randomized 822 patients to receive 25 mg spironolactone daily and 841 to receive placebo. The primary endpoint was death from all causes. Randomization began on March 24, 1995; recruitment was completed on December 31, 1996; follow-up w...
Autores principales: | Wittes, Janet, Palensky, Jolie, Asner, Debra, Julian, Desmond, Boissel, Jean-Pierre, Furberg, Curt D, Kulbertus, Henri, Pocock, Stuart, Roniker, Barbara |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC56203/ https://www.ncbi.nlm.nih.gov/pubmed/11806773 http://dx.doi.org/10.1186/cvm-2-1-059 |
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