Long non-coding RNAs associated with non-small cell lung cancer

Lung cancer, with 80–85% being non-small cell lung cancer (NSCLC), is the leading cause of cancer-related death in both men and women. Long non-coding RNAs (lncRNAs), always defined as non-protein-coding RNA molecules longer than 200 nucleotides, are now thought as a new frontier in the study of hum...

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Autores principales: Zhan, Yuting, Zang, Hongjing, Feng, Juan, Lu, Junmi, Chen, Lingjiao, Fan, Songqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620328/
https://www.ncbi.nlm.nih.gov/pubmed/28978188
http://dx.doi.org/10.18632/oncotarget.20088
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author Zhan, Yuting
Zang, Hongjing
Feng, Juan
Lu, Junmi
Chen, Lingjiao
Fan, Songqing
author_facet Zhan, Yuting
Zang, Hongjing
Feng, Juan
Lu, Junmi
Chen, Lingjiao
Fan, Songqing
author_sort Zhan, Yuting
collection PubMed
description Lung cancer, with 80–85% being non-small cell lung cancer (NSCLC), is the leading cause of cancer-related death in both men and women. Long non-coding RNAs (lncRNAs), always defined as non-protein-coding RNA molecules longer than 200 nucleotides, are now thought as a new frontier in the study of human malignant diseases including NSCLC. As researches continue, increasing number of roles that lncRNAs play in NSCLC has been found, and more and more evidences show lncRNAs have a close relationship with patients’ response to radiochemotherapy or molecular therapy. The aim of this review is to disclose the roles that lncRNAs play in NSCLC and how lncRANs influence the treatment of NSCLC.
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spelling pubmed-56203282017-10-03 Long non-coding RNAs associated with non-small cell lung cancer Zhan, Yuting Zang, Hongjing Feng, Juan Lu, Junmi Chen, Lingjiao Fan, Songqing Oncotarget Review Lung cancer, with 80–85% being non-small cell lung cancer (NSCLC), is the leading cause of cancer-related death in both men and women. Long non-coding RNAs (lncRNAs), always defined as non-protein-coding RNA molecules longer than 200 nucleotides, are now thought as a new frontier in the study of human malignant diseases including NSCLC. As researches continue, increasing number of roles that lncRNAs play in NSCLC has been found, and more and more evidences show lncRNAs have a close relationship with patients’ response to radiochemotherapy or molecular therapy. The aim of this review is to disclose the roles that lncRNAs play in NSCLC and how lncRANs influence the treatment of NSCLC. Impact Journals LLC 2017-08-09 /pmc/articles/PMC5620328/ /pubmed/28978188 http://dx.doi.org/10.18632/oncotarget.20088 Text en Copyright: © 2017 Zhan et al. http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Review
Zhan, Yuting
Zang, Hongjing
Feng, Juan
Lu, Junmi
Chen, Lingjiao
Fan, Songqing
Long non-coding RNAs associated with non-small cell lung cancer
title Long non-coding RNAs associated with non-small cell lung cancer
title_full Long non-coding RNAs associated with non-small cell lung cancer
title_fullStr Long non-coding RNAs associated with non-small cell lung cancer
title_full_unstemmed Long non-coding RNAs associated with non-small cell lung cancer
title_short Long non-coding RNAs associated with non-small cell lung cancer
title_sort long non-coding rnas associated with non-small cell lung cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620328/
https://www.ncbi.nlm.nih.gov/pubmed/28978188
http://dx.doi.org/10.18632/oncotarget.20088
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