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Mechanical signals activate p38 MAPK pathway-dependent reinforcement of actin via mechanosensitive HspB1

Despite the importance of a cell’s ability to sense and respond to mechanical force, the molecular mechanisms by which physical cues are converted to cell-instructive chemical information to influence cell behaviors remain to be elucidated. Exposure of cultured fibroblasts to uniaxial cyclic stretch...

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Detalles Bibliográficos
Autores principales: Hoffman, Laura, Jensen, Christopher C., Yoshigi, Masaaki, Beckerle, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620374/
https://www.ncbi.nlm.nih.gov/pubmed/28768826
http://dx.doi.org/10.1091/mbc.E17-02-0087