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Targeting Host Cell Surface Nucleolin for RSV Therapy: Challenges and Opportunities

Nucleolin (NCL) has been reported as a cellular receptor for the human respiratory syncytial virus (RSV). We studied the effects of re-purposing AS1411, an anti-cancer compound that binds cell surface NCL, as a possible novel strategy for RSV therapy in vitro and in vivo. AS1411 was administered to...

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Detalles Bibliográficos
Autores principales:	Mastrangelo, Peter, Norris, Michael J., Duan, Wenming, Barrett, Edward G., Moraes, Theo J., Hegele, Richard G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620558/ https://www.ncbi.nlm.nih.gov/pubmed/28925950 http://dx.doi.org/10.3390/vaccines5030027

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