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The Binding Effect of Proteins on Medications and Its Impact on Electrochemical Sensing: Antipsychotic Clozapine as a Case Study
Clozapine (CLZ), a dibenzodiazepine, is demonstrated as the optimal antipsychotic for patients suffering from treatment-resistant schizophrenia. Like many other drugs, understanding the concentration of CLZ in a patient’s blood is critical for managing the patients’ symptoms, side effects, and overa...
Autores principales: | Banis, George E., Winkler, Thomas, Barton, Patricia, Chocron, Sheryl E., Kim, Eunkyoung, Kelly, Deanna L., Payne, Gregory F., Ben-Yoav, Hadar, Ghodssi, Reza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620613/ https://www.ncbi.nlm.nih.gov/pubmed/28763030 http://dx.doi.org/10.3390/ph10030069 |
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