Complexes of Oligoribonucleotides with D-Mannitol Inhibit Hemagglutinin–Glycan Interaction and Suppress Influenza A Virus H1N1 (A/FM/1/47) Infectivity In Vitro

The influenza virus hemagglutinin (HA) mediates both receptor (glycan) binding and membrane fusion for cell entry and has been the basis for subtyping influenza viruses. The oligoribonucleotides-d-mannitol (ORNs-d-M) complexes possess an anti-influenza activity in vitro and in vivo. In the present s...

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Detalles Bibliográficos
Autores principales: Melnichuk, Nataliia, Semernikova, Larisa, Tkachuk, Zenoviy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620615/
https://www.ncbi.nlm.nih.gov/pubmed/28792452
http://dx.doi.org/10.3390/ph10030071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620615/
https://www.ncbi.nlm.nih.gov/pubmed/28792452
http://dx.doi.org/10.3390/ph10030071

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