Cargando…

One-Step Facile Synthesis of Aptamer-Modified Graphene Oxide for Highly Specific Enrichment of Human A-Thrombin in Plasma

The enrichment of low-abundance proteins in complex biological samples plays an important role in clinical diagnostics and biomedical research. This work reports a novel one-step method for the synthesis of aptamer-modified graphene oxide (GO/Apt) nanocomposites, without introducing the use of gold,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Yuan, Tan, Siyuan, Liang, Qionglin, Ding, Mingyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621013/ https://www.ncbi.nlm.nih.gov/pubmed/28902155 http://dx.doi.org/10.3390/s17091986

Ejemplares similares

Supramolecular Aptamers on Graphene Oxide for Efficient Inhibition of Thrombin Activity
por: Lin, Ting-Xuan, et al.
Publicado: (2019)

Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity
por: Dolot, Rafal, et al.
Publicado: (2018)

Facile One-Step Synthesis and Enhanced Optical Nonlinearity of Graphene-γMnS
por: Zhang, Zhihao, et al.
Publicado: (2019)

Thrombin binding aptamer G-quadruplex stabilized by pyrene-modified nucleotides
por: Kovačič, Matic, et al.
Publicado: (2020)

One-Step Synthesis of N-doped Graphene Quantum Sheets from Monolayer Graphene by Nitrogen Plasma
por: Moon, Joonhee, et al.
Publicado: (2014)

Thrombin–aptamer recognition: a revealed ambiguity
por: Russo Krauss, Irene, et al.
Publicado: (2011)

Aptamer Based Microsphere Biosensor for Thrombin Detection
por: Zhu, Hongying, et al.
Publicado: (2006)

One-Step Photochemical Immobilization of Aptamer on Graphene for Label-Free Detection of NT-proBNP
por: Nekrasov, Nikita, et al.
Publicado: (2022)

High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity
por: Russo Krauss, Irene, et al.
Publicado: (2012)

Direct Detection of Thrombin Binding to 8-Bromodeoxyguanosine-Modified Aptamer: Effects of Modification on Affinity and Kinetics
por: Goji, Shou, et al.
Publicado: (2011)

Thrombin Aptamer-Modified Metal–Organic Framework Nanoparticles: Functional Nanostructures for Sensing Thrombin and the Triggered Controlled Release of Anti-Blood Clotting Drugs
por: Chen, Wei-Hai, et al.
Publicado: (2019)

Development and Optimization of a Thrombin Sandwich Aptamer Microarray
por: Meneghello, Anna, et al.
Publicado: (2012)

Alpha-Deoxyguanosine to Reshape the Alpha-Thrombin Binding Aptamer
por: Kolganova, Natalia A., et al.
Publicado: (2023)

A new modified thrombin binding aptamer containing a 5′–5′ inversion of polarity site
por: Martino, Luigi, et al.
Publicado: (2006)

Thrombin-Binding Aptamer Quadruplex Formation: AFM and Voltammetric Characterization
por: Diculescu, Victor Constantin, et al.
Publicado: (2010)

Comparison of the ‘Chemical’ and ‘Structural’ Approaches to the Optimization of the Thrombin-Binding Aptamer
por: Tatarinova, Olga, et al.
Publicado: (2014)

Facile One-Step Sonochemical Synthesis and Photocatalytic Properties of Graphene/Ag(3)PO(4) Quantum Dots Composites
por: Reheman, Abulajiang, et al.
Publicado: (2018)

Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads
por: Benigno, Daniela, et al.
Publicado: (2022)

Novel isoguanine derivative of unlocked nucleic acid—Investigations of thermodynamics and biological potential of modified thrombin binding aptamer
por: Kotkowiak, Weronika, et al.
Publicado: (2018)

Experimental and mathematical evidence that thrombin-binding aptamers form a 1 aptamer:2 protein complex
por: Mears, Kepler S, et al.
Publicado: (2018)

Electrical Stimulus Controlled Binding/Unbinding of Human Thrombin-Aptamer Complex
por: Gosai, Agnivo, et al.
Publicado: (2016)

The Evaluation of Pharmacodynamics and Pharmacokinetics of Anti-thrombin DNA Aptamer RA-36
por: Zavyalova, Elena, et al.
Publicado: (2017)

Etched Fiber Bragg Grating Biosensor Functionalized with Aptamers for Detection of Thrombin
por: Bekmurzayeva, Aliya, et al.
Publicado: (2018)

Structural and Binding Effects of Chemical Modifications on Thrombin Binding Aptamer (TBA)
por: Valsangkar, Vibhav, et al.
Publicado: (2021)

The Regioselective Conjugation of the 15-nt Thrombin Aptamer with an Optimized Tripeptide Sequence Greatly Increases the Anticoagulant Activity of the Aptamer
por: Varizhuk, Irina V., et al.
Publicado: (2023)

Impact of the Position of the Chemically Modified 5-Furyl-2′-Deoxyuridine Nucleoside on the Thrombin DNA Aptamer–Protein Complex: Structural Insights into Aptamer Response from MD Simulations
por: Seelam Prabhakar, Preethi, et al.
Publicado: (2019)

Facile One-Step Fabrication of Phthalocyanine–Graphene–Bacterial–Cellulose Nanocomposite with Superior Catalytic Performance
por: Hong, Qiulin, et al.
Publicado: (2020)

Concise, Single‐Step Synthesis of Sulfur‐Enriched Graphene: Immobilization of Molecular Clusters and Battery Applications
por: Omachi, Haruka, et al.
Publicado: (2020)

Facile One-Step Electrodeposition Preparation of Cationic Pillar[6]arene-Modified Graphene Films on Glassy Carbon Electrodes for Enhanced Electrochemical Performance
por: Duan, Qunpeng, et al.
Publicado: (2020)

Evaluation of Antithrombotic Activity of Thrombin DNA Aptamers by a Murine Thrombosis Model
por: Zavyalova, Elena, et al.
Publicado: (2014)

Development of a Multiplex Sandwich Aptamer Microarray for the Detection of VEGF(165) and Thrombin
por: Sosic, Alice, et al.
Publicado: (2013)

Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers
por: Pica, Andrea, et al.
Publicado: (2017)

Putative Mechanisms Underlying High Inhibitory Activities of Bimodular DNA Aptamers to Thrombin
por: Zavyalova, Elena G., et al.
Publicado: (2019)

Construction of a Bivalent Thrombin Binding Aptamer and Its Antidote with Improved Properties
por: Hughes, Quintin W., et al.
Publicado: (2017)

Recognition Interface of the Thrombin Binding Aptamer Requires Antiparallel Topology of the Quadruplex Core
por: Svetlova, Julia, et al.
Publicado: (2021)

Anticoagulant Oligonucleotide–Peptide Conjugates: Identification of Thrombin Aptamer Conjugates with Improved Characteristics
por: Tsvetkov, Vladimir B., et al.
Publicado: (2022)

A neutralizable dimeric anti-thrombin aptamer with potent anticoagulant activity in mice
por: Nagano, Masanobu, et al.
Publicado: (2023)

One-Step Plasma Synthesis of Nitrogen-Doped Carbon Nanomesh
por: Vesel, Alenka, et al.
Publicado: (2021)

One-Step Synthesis of Pt/Graphene Composites from Pt Acid Dissolved Ethanol via Microwave Plasma Spray Pyrolysis
por: Jo, Eun Hee, et al.
Publicado: (2016)

Facile one-step hydrothermal synthesis of monolayer and turbostratic bilayer n-doped graphene quantum dots using sucrose as a carbon source
por: Ruammaitree, Akkawat, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s40n0q9ipdm4au14ca6cr85ggc