Cargando…

RNA splicing process analysis for identifying antisense oligonucleotide inhibitors with padlock probe-based isothermal amplification

RNA splicing, which mainly involves two transesterification steps, is a fundamental process of gene expression and its abnormal regulation contributes to serious genetic diseases. Antisense oligonucleotides (ASOs) are genetic control tools that can be used to specifically control genes through alter...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Xiaojun, Deng, Ruijie, Wang, Lida, Zhang, Kaixiang, Li, Jinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621167/
https://www.ncbi.nlm.nih.gov/pubmed/28989608
http://dx.doi.org/10.1039/c7sc01336a