Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil

We isolated East/Central/South African genotype chikungunya virus during the 2016 epidemic in Rio de Janeiro, Brazil. Genome sequencing revealed unique mutations in the nonstructural protein 4 (NSP4-A481D) and envelope protein 1 (E1-K211T). Moreover, all Brazil East/Central/South isolates shared the...

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Autores principales: Cunha, Marcela S., Cruz, Nádia V.G., Schnellrath, Laila C., Medaglia, Maria Luiza Gomes, Casotto, Michele E., Albano, Rodolpho M., Costa, Luciana J., Damaso, Clarissa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621531/
https://www.ncbi.nlm.nih.gov/pubmed/28930027
http://dx.doi.org/10.3201/eid2310.161855
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author Cunha, Marcela S.
Cruz, Nádia V.G.
Schnellrath, Laila C.
Medaglia, Maria Luiza Gomes
Casotto, Michele E.
Albano, Rodolpho M.
Costa, Luciana J.
Damaso, Clarissa R.
author_facet Cunha, Marcela S.
Cruz, Nádia V.G.
Schnellrath, Laila C.
Medaglia, Maria Luiza Gomes
Casotto, Michele E.
Albano, Rodolpho M.
Costa, Luciana J.
Damaso, Clarissa R.
author_sort Cunha, Marcela S.
collection PubMed
description We isolated East/Central/South African genotype chikungunya virus during the 2016 epidemic in Rio de Janeiro, Brazil. Genome sequencing revealed unique mutations in the nonstructural protein 4 (NSP4-A481D) and envelope protein 1 (E1-K211T). Moreover, all Brazil East/Central/South isolates shared the exclusive mutations E1-M407L and E2-A103T.
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spelling pubmed-56215312017-10-07 Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil Cunha, Marcela S. Cruz, Nádia V.G. Schnellrath, Laila C. Medaglia, Maria Luiza Gomes Casotto, Michele E. Albano, Rodolpho M. Costa, Luciana J. Damaso, Clarissa R. Emerg Infect Dis Research Letter We isolated East/Central/South African genotype chikungunya virus during the 2016 epidemic in Rio de Janeiro, Brazil. Genome sequencing revealed unique mutations in the nonstructural protein 4 (NSP4-A481D) and envelope protein 1 (E1-K211T). Moreover, all Brazil East/Central/South isolates shared the exclusive mutations E1-M407L and E2-A103T. Centers for Disease Control and Prevention 2017-10 /pmc/articles/PMC5621531/ /pubmed/28930027 http://dx.doi.org/10.3201/eid2310.161855 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Cunha, Marcela S.
Cruz, Nádia V.G.
Schnellrath, Laila C.
Medaglia, Maria Luiza Gomes
Casotto, Michele E.
Albano, Rodolpho M.
Costa, Luciana J.
Damaso, Clarissa R.
Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil
title Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil
title_full Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil
title_fullStr Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil
title_full_unstemmed Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil
title_short Autochthonous Transmission of East/Central/South African Genotype Chikungunya Virus, Brazil
title_sort autochthonous transmission of east/central/south african genotype chikungunya virus, brazil
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621531/
https://www.ncbi.nlm.nih.gov/pubmed/28930027
http://dx.doi.org/10.3201/eid2310.161855
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