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Myocardial wall stiffening in a mouse model of persistent truncus arteriosus

BACKGROUND: Genetic and epigenetic programs regulate dramatic structural changes during cardiac morphogenesis. Concurrent biomechanical forces within the heart created by blood flow and pressure in turn drive downstream cellular, molecular and genetic responses. Thus, a genetic-morphogenetic-biomech...

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Detalles Bibliográficos
Autores principales: Buffinton, Christine Miller, Benjamin, Alyssa K., Firment, Ashley N., Moon, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621674/
https://www.ncbi.nlm.nih.gov/pubmed/28961240
http://dx.doi.org/10.1371/journal.pone.0184678