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Sp5 induces the expression of Nanog to maintain mouse embryonic stem cell self-renewal

Activation of signal transducer and activator of transcription 3 (STAT3) by leukemia inhibitory factor (LIF) maintains mouse embryonic stem cell (mESC) self-renewal. Our previous study showed that trans-acting transcription factor 5 (Sp5), an LIF/STAT3 downstream target, supports mESC self-renewal....

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Detalles Bibliográficos
Autores principales:	Tang, Ling, Wang, Manman, Liu, Dahai, Gong, Mengting, Ying, Qi-Long, Ye, Shoudong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621696/ https://www.ncbi.nlm.nih.gov/pubmed/28961274 http://dx.doi.org/10.1371/journal.pone.0185714

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