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Chronic administration of mitochondrion-targeted peptide SS-31 prevents atherosclerotic development in ApoE knockout mice fed Western diet

BACKGROUND: Oxidative stress and inflammatory factors are deeply involved in progression of atherosclerosis. Mitochondrion-targeted peptide SS-31, selectively targeting to mitochondrial inner membrane reacting with cardiolipin, has been reported to inhibit ROS generation and mitigate inflammation. T...

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Detalles Bibliográficos
Autores principales:	Zhang, Meng, Zhao, Hongting, Cai, Jing, Li, Huihui, Wu, Qi, Qiao, Tong, Li, Kuanyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621700/ https://www.ncbi.nlm.nih.gov/pubmed/28961281 http://dx.doi.org/10.1371/journal.pone.0185688

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