Cargando…

Ultrasensitive tumour-penetrating nanosensors of protease activity

The ability to identify cancer lesions with endogenous biomarkers is currently limited to tumours ~1 cm in diameter. We recently reported an exogenously administered tumour-penetrating nanosensor that sheds, in response to tumour-specific proteases, peptide fragments that can then be detected in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Ester J., Dudani, Jaideep S., Bhatia, Sangeeta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621765/
https://www.ncbi.nlm.nih.gov/pubmed/28970963
http://dx.doi.org/10.1038/s41551-017-0054