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Enhanced HIF2α expression during human trophoblast differentiation into syncytiotrophoblast suppresses transcription of placental growth factor

Placental growth factor (PlGF), abundantly produced from trophoblasts is involved in placental angiogenesis. The regulatory mechanism of its expression is poorly understood. Hypoxia inducible factors (HIFs) are centrally involved in the modulation of cellular function in response to low oxygen condi...

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Detalles Bibliográficos
Autores principales:	Fujii, Tatsuya, Nagamatsu, Takeshi, Morita, Kazuki, Schust, Danny J., Iriyama, Takayuki, Komatsu, Atsushi, Osuga, Yutaka, Fujii, Tomoyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622029/ https://www.ncbi.nlm.nih.gov/pubmed/28963486 http://dx.doi.org/10.1038/s41598-017-12685-w

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