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Supraspinal-selective TRPV1 desensitization induced by intracerebroventricular treatment with resiniferatoxin

The transient receptor potential vanilloid type 1 (TRPV1) is a thermosensitive cation channel that triggers heat pain in the periphery. Long-term desensitization of TRPV1, which can be induced by excess amounts of agonists, has been a method for investigating the physiological relevance of TRPV1-con...

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Detalles Bibliográficos
Autores principales: Fukushima, Akihiro, Mamada, Kizuku, Iimura, Aki, Ono, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622082/
https://www.ncbi.nlm.nih.gov/pubmed/28963471
http://dx.doi.org/10.1038/s41598-017-12717-5