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Supraspinal-selective TRPV1 desensitization induced by intracerebroventricular treatment with resiniferatoxin
The transient receptor potential vanilloid type 1 (TRPV1) is a thermosensitive cation channel that triggers heat pain in the periphery. Long-term desensitization of TRPV1, which can be induced by excess amounts of agonists, has been a method for investigating the physiological relevance of TRPV1-con...
Autores principales: | Fukushima, Akihiro, Mamada, Kizuku, Iimura, Aki, Ono, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622082/ https://www.ncbi.nlm.nih.gov/pubmed/28963471 http://dx.doi.org/10.1038/s41598-017-12717-5 |
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