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Methylene blue inhibits NLRP3, NLRC4, AIM2, and non-canonical inflammasome activation

Methylene blue (MB), which has antioxidant, anti-inflammatory, neuroprotective, and mitochondria protective effects, has been widely used as a dye and medication. However, the effect of MB on inflammasome activation has not yet been studied. Inflammasomes are multi-protein complexes that induce matu...

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Detalles Bibliográficos
Autores principales: Ahn, Huijeong, Kang, Seung Goo, Yoon, Sung-il, Ko, Hyun-Jeong, Kim, Pyeung-Hyeun, Hong, Eui-Ju, An, Beum-Soo, Lee, Eunsong, Lee, Geun-Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622101/
https://www.ncbi.nlm.nih.gov/pubmed/28963531
http://dx.doi.org/10.1038/s41598-017-12635-6